There are many misconceptions about herpes. Discover the differences between the HSV-1 virus and the HSV-2 virus. There are two types of herpes: HSV-1 (oral herpes) and HSV-2 (genital herpes). How the Latest Workouts Help Manage Type 2 Diabetes. Complete information about Herpes Simplex Type II, including signs and symptoms; conditions that suggest it; contributing risk factors; recommendations. The human herpes viruses, which include Herpes simplex virus types 1 and 2, human cytomegalovirus, Varicella-Zoster virus, and the Epstein-Barr Virus, either cause or are associated with a whole spectrum of diseases ranging from infectious mononucleosis to malignancies and mental retardation. While there is no cure, the frequency and severity of attacks can be reduced.