To test his hypothesis, VanElzakker suggests that vagus nerve biopsy samples should be sought from CFS patients who have died prematurely from other causes. Herpesvirus infections of the trigeminal nerve cause shingles. Do herpesvirus infections of the vagus nerve cause chronic fatigue syndrome? Chronic fatigue syndrome from vagus nerve infection: A psychoneuroimmunological hypothesis.
How did you come to found the HHV-6 Foundation? Lipkin used a herpesvirus consensus PCR that has about the same level of sensitivity that you would find at a commercial laboratory, and those labs rarely if ever find viral DNA in the plasma of CFS/ME patients. Michael VanElzakker’s Vagus Nerve Infection Hypothesis (VNIH) for chronic fatigue syndrome proposes that a difficult-to-detect herpesvirus such as HHV6 (or other) infection of the sensory ganglia associated with the vagus nerve could trigger an ongoing case of sickness behavior’; e. Chronic Fatigue from Vagus Nerve Infection: A Psychoneuroimmunological Hypothes. How is it that say an infection in your lungs can cause you to have all these changes in your subjective experience, like feeling really exhausted and sore? Well, the vagus nerve is really important for that. Increased antibodies in people with Chronic Fatigue Syndrome, a history of severe herpes virus infection predicts Chronic Fatigue Syndrome. Chronic hepatitis B and hepatitis C viral infections can produce symptoms that resemble those of ME/CFS. There are no hard and fast rules for chronic fatigue syndrome treatment, and you may wish to follow different courses of action to those given here. Reports Cidofovir Effective in Treating Herpesvirus Infected ME/CFS Patients. 1 One speculative theory of how jaw misalignment might create ME/CFS symptoms centers on the fact that inflammation around the trigeminal or vagus nerves can trigger what is known as the sickness behavior response, and this response has symptoms very similar to those of ME/CFS.
Chronic fatigue syndrome (CFS) is an often-debilitating condition of unknown origin. The vagus nerve infection hypothesis of CFS contends that CFS symptoms are a pathologically exaggerated version of normal sickness behavior that can occur when sensory vagal ganglia or paraganglia are themselves infected with any virus or bacteria. As it & 145;wanders& 146; through the body it comes into contact with virus havens such as the esophagus, stomach, lungs and spleen, all of which have likely at one time or another harbored the herpesviruses (HHV6, HHV-5 cytomegalovirus, HHV-4 Epstein-Barr virus ) that have been thought to be associated with ME/CFS for decades. The vagus nerve can help reduce pain and this is the mechanism by which estradiol reduces pain in certain circumstances (R). -explain-vagus-nerve-infection-chronic-fatigue-syndrome/ Cheers. Chronic fatigue (CFS) is an interesting concept as a condition that brings as much frustration as relief to many. Poor Methylation: According to Rich van Konynenburg, poor methylation is a major cause of fatigue. The methylation cycle is essential for cell mediated immune function and blockages here will mean that infections will not be adequately dealt with.
The Lipkin Study, The Vagus Nerve Infection Hypothesis And HHV-6: Kristin Loomis Of The HHV-6 Foundation Talks
Many experts believe that chronic fatigue syndrome (CFS) has several root causes including some viruses. There was also a medical hypotheses research paper posted here recently that proposed that the Vagus nerve might have become infected giving rise to many of the unpleasant M. Fibromyalgia (FM) is a chronic pain disorder with unknown etiology and unclear pathoph. More Got it!. Chronic fatigue syndrome from vagus nerve infection: A. Theories abound about the causes of chronic fatigue syndrome. Chronic hyperventilation can cause an imbalance in oxygen and carbon dioxide, which may produce chest pain, faintness, numbness in the fingers and toes, and motor impairment. One study found that after CFS patients exercise, they exhibit slight abnormalities in the activity of the vagus nerves on the heart. Briefly, acute, prolonged or persistent infections lead to chronic activation of the immune system and subsequent elevated levels of pro-inflammatory cytokines and O&NS leading in turn to O&NS damage to self epitopes and recruitment of autoreactive T cells. This apparent paradox can be resolved by the fact that the afferent sensory fibres of the vagus nerve are able to detect minimally elevated levels of cytokines and relay the information indicating the presence of peripheral immune activation to the brain via ascending fibres 147,148. J. Multiple co-infections (Mycoplasma, Chlamydia, human herpesvirus-6) in blood of chronic fatigue syndrome patients: association with signs and symptoms. Small fiber neuropathy possibly caused by immune dysregulation has been found. Pridgen’s provisional patent proposes this treatment will work for chronic fatigue syndrome, irritable bowel syndrome, chronic pain, chronic headache, chronic neck pain, chronic back pain, chronic depression, chronic clinical anxiety disorder, post-traumatic stress disorder (PTSD), brain fog, cognitive dysfunction and chronic interstitial cystitis. Now, Pridgen and Duffy are testing gut samples for herpes virus simplex in their study.
Chronic Fatigue Syndrome From Vagus Nerve Infection: A Psychoneuroimmunological Hypothesis
Symptoms typical of sickness behavior are described above. The third pathway involves the activation of neurons by proinflammatory cytokines via the vagus nerve and catecholaminergic circuits of the sympathetic nervous system (SNS) 12. Other infections that are associated with this disorder are, among others, human herpesvirus. Chronic fatigue syndrome (also called myalgic encephalomyelitis in England) does not appear to be new. Some experts believe that in CFS patients, a virus or infection may cause injury to the central nervous system that results in the hypotension abnormality. One study found that after CFS patients exercise, they exhibit slight abnormalities in the activity of the vagus nerves on the heart; the vagus nerves run down each side of the neck and end at the intestines and affect many bodily functions. Many of the patients who present with symptoms of an irritated vagus nerve have what could be described as a Gall Bladder and Heart Complex in Chinese medicine. According to NIH research, Foot reflexology can increase vagal modulation, and decrease sympathetic modulation. Chronic fatigue syndrome: a herpes virus infection of the vagus nerve? However, the virus can still be transmitted even if you are not showing symptoms.
Novel Approach to Herpesvirus Infections Could Reap Dividends for CFS. Theory To Explain Them All? The Vagus Nerve Infection Hypothesis for CFS. .com/2013/12/one-theory-explain-vagus-nerve-infection-chronic-fatigue-syndrome/.